14941-08-3

14941-08-3 structure

Name: Poncirin
Chemical Name: (2S)-poncirin
CAS Number: 14941-08-3
Molecular Formula: C₂₈H₃₄O₁₄
Molecular Weight: 594.561
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-03-26 08:00:00
Modify Date: 2024-01-01 23:48:25
Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models[1].

Name	(2S)-poncirin
Synonyms	(2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one Einecs 239-020-1 Neohesperidoside isosakuranetin-7 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (2S)- Poncirin (2S)-5-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside (2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-méthoxyphényl)-2,3-dihydro-4H-chromén-4-one Isosakuranetin 7-O-neohesperidoside (S)-7-((2-O-(6-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one ISOSAKURANETIN-7-NEOHESPERIDOSIDE (2S)-7-{[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-on (S)-7-((2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one 4'-O-Methylnaringin ISOSAKURANETIN-7-O-NEOHESPERIDOSID (2S)-5-Hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside Isosakuranetin-7-O-neohesperidoside Citrifolioside

Description	Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Inflammation/Immunology
In Vivo	Poncirin (intraperitoneal administration; 30 mg/kg) markedly reduces the pain behavior in both acetic acid-induced visceral pain and formalin-induced tonic pain models inComplete Freund’s Adjuvant (CFA)-induced inflammatory pain model[1].
References	[1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.

Density	1.6±0.1 g/cm3
Boiling Point	900.1±65.0 °C at 760 mmHg
Melting Point	210ºC
Molecular Formula	C₂₈H₃₄O₁₄
Molecular Weight	594.561
Flash Point	296.5±27.8 °C
Exact Mass	594.194885
PSA	214.06000
LogP	3.39
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.678

Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

23643-72-3

14941-08-3

Literature: Chen, Lao-Jer; Hrazdina, Geza Phytochemistry (Elsevier), 1981 , vol. 20, p. 297 - 304

123-11-5

14941-08-3

Literature: Phytochemistry (Elsevier), , vol. 20, p. 297 - 304

23643-71-2

14941-08-3

Literature: Phytochemistry (Elsevier), , vol. 20, p. 297 - 304

Precursor 3
23643-72-3 123-11-5 23643-71-2
DownStream 0