Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Triethylenetetramine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Triethylenetetramine
Price: ￥118.0/500ml
Purity: 65.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Triethylenetetramine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Trientine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

112-24-3

112-24-3 structure

Name: Triethylenetetramine
Chemical Name: 2,2,2-tetramine
CAS Number: 112-24-3
Molecular Formula: C₆H₁₈N₄
Molecular Weight: 146.234
Catalog: API Special medicine Antidote
Create Date: 2018-02-04 08:00:00
Modify Date: 2024-01-02 16:02:41

Name	2,2,2-tetramine
Synonyms	EINECS 203-950-6 1,2-Ethanediamine, N,N-bis(2-aminoethyl)- Trientine N,N'-Bis(2-aminoethyl)-1,2-ethanediamine N,N'-Bis(2-aminoethyl)ethane-1,2-diamine TRIETHYLENETETRAAMINE Triethylenetetramine (TETA) N,N-Di(2-Aminoethyl)Ethylenediamine Triethylenetetramine DEH 24 EPH 925 TETA N,N'-Di(2-aminoethyl)ethylenediamine 1,8-diamino-3,6-diazaoctane 2,2,2-tetramine N1,N1'-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) MFCD00008169 triethylene tetramine

Density	1.0±0.1 g/cm3
Boiling Point	266.5±0.0 °C at 760 mmHg
Melting Point	12 °C(lit.)
Molecular Formula	C₆H₁₈N₄
Molecular Weight	146.234
Flash Point	143.3±0.0 °C
Exact Mass	146.153152
PSA	76.10000
LogP	-2.18
Vapour density	~5 (vs air)
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.490
Stability	Syable. Incompatible with strong oxidizing agents, strong acids.
Water Solubility	SOLUBLE
Freezing Point	12℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YE6650000

CHEMICAL NAME :: Triethylenetetramine

CAS REGISTRY NUMBER :: 112-24-3

BEILSTEIN REFERENCE NO. :: 0605448

LAST UPDATED :: 199710

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C6-H18-N4

MOLECULAR WEIGHT :: 146.28

WISWESSER LINE NOTATION :: Z2M2M2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 468 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 805 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 9130 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - homeostasis Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 17430 mg/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 8715 mg/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 3667 mg/kg

SEX/DURATION :: female 10-56 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 1 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,31,1994 *** REVIEWS *** TOXICOLOGY REVIEW JJOMDZ JOM, Journal of Occupational Medicine. (American Occupational Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606) V.10- 1968- Volume(issue)/page/year: 15,808,1973 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 12,601,1978 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 1 ppm (6 mg/m3);STEL 2 ppm (12 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82037 No. of Facilities: 1982 (estimated) No. of Industries: 37 No. of Occupations: 44 No. of Employees: 14389 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82037 No. of Facilities: 7057 (estimated) No. of Industries: 96 No. of Occupations: 88 No. of Employees: 165511 (estimated) No. of Female Employees: 20726 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H312-H314-H317-H412
Precautionary Statements	P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive
Risk Phrases	R21;R34;R43;R52/53
Safety Phrases	S26-S36/37/39-S45-S61
RIDADR	UN 2259 8/PG 2
WGK Germany	2
RTECS	YE6650000
Packaging Group	II
Hazard Class	8
HS Code	29212900

Precursor 8
10526-69-9 540-61-4 107-06-2 50-00-0
74-90-8 107-15-3 151-56-4 111-40-0
DownStream 10
52667-88-6 141998-21-2 281193-14-4 295-14-7
24426-12-8 869-52-3 110-85-0 280-57-9
294-90-6 140-31-8

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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