104778-16-7

104778-16-7 structure

Name: 4-O-Methylsappanol
Chemical Name: (3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
CAS Number: 104778-16-7
Molecular Formula: C₁₇H₁₈O₆
Molecular Weight: 318.321
Catalog: Natural product Flavonoids
Create Date: 2016-12-12 20:48:07
Modify Date: 2024-01-05 09:53:25
4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 µM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2].

Name	(3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
Synonyms	4-O-Methyl-sappanol 2H-1-Benzopyran-3,7-diol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-4-methoxy-, (3R,4S)- 1,2,5-trideoxy-1,5-imino-D-erythritol (3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol cis-Piperidin-3,4-diol

Description	4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 µM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	4-O-Methylsappanol 对 HMV-II 细胞显示出中等的细胞毒性，IC50 值为 20.2 µM[2]。
References	[1]. V L Niranjan Reddy, et al. Inhibitory activity of homoisoflavonoids from Caesalpinia sappan against Beauveria bassiana. Fitoterapia. 2003 Sep;74(6):600-2. [2]. Kaoru Mitani, et al. Suppression of melanin synthesis by the phenolic constituents of sappanwood (Caesalpinia sappan). Planta Med. 2013 Jan;79(1):37-44.

Hazard Codes	Xi

Precursor 0
DownStream 1
474-07-7