4-O-Methylsappanol

Modify Date: 2024-01-05 09:53:25

4-O-Methylsappanol Structure
4-O-Methylsappanol structure
Common Name 4-O-Methylsappanol
CAS Number 104778-16-7 Molecular Weight 318.321
Density 1.5±0.1 g/cm3 Boiling Point 564.0±50.0 °C at 760 mmHg
Molecular Formula C17H18O6 Melting Point N/A
MSDS N/A Flash Point 294.9±30.1 °C

 Use of 4-O-Methylsappanol


4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 µM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2].

 Names

Name (3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
Synonym More Synonyms

 4-O-Methylsappanol Biological Activity

Description 4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 µM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2].
Related Catalog
In Vitro 4-O-Methylsappanol 对 HMV-II 细胞显示出中等的细胞毒性,IC50 值为 20.2 µM[2]。
References

[1]. V L Niranjan Reddy, et al. Inhibitory activity of homoisoflavonoids from Caesalpinia sappan against Beauveria bassiana. Fitoterapia. 2003 Sep;74(6):600-2.  

[2]. Kaoru Mitani, et al. Suppression of melanin synthesis by the phenolic constituents of sappanwood (Caesalpinia sappan). Planta Med. 2013 Jan;79(1):37-44.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 564.0±50.0 °C at 760 mmHg
Molecular Formula C17H18O6
Molecular Weight 318.321
Flash Point 294.9±30.1 °C
Exact Mass 318.110352
PSA 99.38000
LogP 1.19
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.691

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

4-O-Methyl-sappanol
2H-1-Benzopyran-3,7-diol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-4-methoxy-, (3R,4S)-
1,2,5-trideoxy-1,5-imino-D-erythritol
(3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
cis-Piperidin-3,4-diol
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