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86227-47-6

86227-47-6 structure
86227-47-6 structure

Name ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate
Synonyms Epadel
5,8,11,14,17-Eicosapentaenoic acid, ethyl ester, (all-Z)-
all-cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester
Eicosapentaenoic acid-D5 ethyl ester
Ethyl icosapentate
ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
E-EPA
AMR 101
ethyl icosapentaenoate
ethyl (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate
(Z,Z,Z,Z,Z)-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
5,8,11,14,17-Eicosapentaenoic acid, ethyl ester, (5Z,8Z,11Z,14Z,17Z)-
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
Ethyl all cis-5,8,11,14,17-Icosapentaenoate
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate
ethyl all-cis-5,8,11,14,17-icosapentaenoate
ethyl eicosapentaenoate
Ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
EICOSAPENTAENOIC ACID ETHYL ESTER
Timnodonic acid ethyl ester
(5Z,8Z,11Z,14Z,17Z)-Eicosapetaenoic acid ethyl ester
ALL CIS-5,8,11,14,17-EICOSAPENTANOIC ACID ETHYL ESTER
Ethyl (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-icosapentaenoate
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
Ethyl (all cis)-5,8,11,14,17-icosapentaenoate
(all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl ester
Eicosapentaenoic Acid ethyl este
AMR-101
Eicosapentaenoic acid, ethyl ester
Vascepa
OMEGA-3-ACID ESTERS (EPA shown)
Ethyl eicosapentaenoic acid
Icosapent ethyl
MFCD00673476
Eicosapentaenoic acid (ethyl ester)
Density 0.9±0.1 g/cm3
Boiling Point 417.0±34.0 °C at 760 mmHg
Molecular Formula C22H34O2
Molecular Weight 330.504
Flash Point 103.1±24.0 °C
Exact Mass 330.255890
PSA 26.30000
LogP 7.32
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.496
Storage condition Refrigerator
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate (stabilized Revision number: 6
with Tocopherols)
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:Ethyl all cis-5,8,11,14,17-Eicosapentaenoate (stabilized with Tocopherols)

Revision number:6

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDSNot classified
GHS label elements, including precautionary statements
Pictograms or hazard symbolsNone
Signal wordNo signal word
Hazard statementsNone
Precautionary statements:None

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance
Substance/mixture:
Components:Ethyl all cis-5,8,11,14,17-Eicosapentaenoate (stabilized with Tocopherols)
>65.0%(GC)
Percent:
CAS Number:86227-47-6
all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester (stabilized with Tocopherols) ,
Synonyms:
EPA Ethyl Ester (stabilized with Tocopherols) , Ethyl all cis-5,8,11,14,17-
Icosapentaenoate (stabilized with Tocopherols)
Chemical Formula:C22H34O2

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Get medical advice/attention if you feel unwell. Rinse mouth.
Ingestion:
Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Dry chemical, foam, carbon dioxide.
Suitable extinguishing
media:
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
(stabilized with Tocopherols)

Section5. FIRE-FIGHTING MEASURES
Unsuitable extinguishing Water (It may scatter and spread fire.)
media:
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Ensure adequate ventilation. Entry to non-involved personnel should be controlled
emergency procedures: around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Absorb spilled material in a suitable absorbent (e.g. rag, dry sand, earth, saw-dust).
containment and cleaning In case of large amount of spillage, contain a spill by bunding. Adhered or collected
up: material should be promptly disposed of, in accordance with appropriate laws and
regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent generation of vapour or mist. Wash hands and face thoroughly after
handling.
Use a ventilation, local exhaust if vapour or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a refrigerator.
Store under inert gas.
Store away from incompatible materials such as oxidizing agents.
Heat-sensitive, Air-sensitive
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Vapor respirator. Follow local and national regulations.
Protective gloves.
Hand protection:
Eye protection:Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Liquid
Form:Clear
Colorless - Yellow
Colour:
Odour:No data available
pH: No data available
Melting point/freezing point:No data available
No data available
Boiling point/range:
Flash point:No data available
Flammability or explosive
limits:
Lower:No data available
Upper:No data available
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
(stabilized with Tocopherols)

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Relative density:0.91
Solubility(ies):
[Water]No data available
No data available
[Other solvents]

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide
products:

Section11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
IARC =
NTP =No data available
No data available
Reproductive toxicity:

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
Algae:No data available
Persistence / degradability: No data available
BioaccumulativeNo data available
potential(BCF):
Mobility in soil
Log Pow:No data available
Soil adsorption (Koc):No data available
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to burn in a chemical
incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when
disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
UN-No:Not listed

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
(stabilized with Tocopherols)


SECTION 16 - ADDITIONAL INFORMATION
N/A
Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 2916190090

~64%

86227-47-6 structure

86227-47-6

Literature: Takahashi, Yoshinori; Tanaka, Kaori; Murakami, Mototake; Kawanari, Masami; Kawasaki, Yoshihiro; et al. Bioscience, Biotechnology, and Biochemistry, 1995 , vol. 59, # 5 p. 809 - 812

~99%

86227-47-6 structure

86227-47-6

Literature: Morrone; D'Antona; Biondi; Lambusta; Nicolosi Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 173 - 176

~98%

86227-47-6 structure

86227-47-6

Literature: Morrone; D'Antona; Biondi; Lambusta; Nicolosi Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 173 - 176
HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%