6493-06-7

6493-06-7 structure
6493-06-7 structure
  • Name: Lisofylline
  • Chemical Name: (±)-Lisofylline
  • CAS Number: 6493-06-7
  • Molecular Formula: C13H20N4O3
  • Molecular Weight: 280.323
  • Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
  • Create Date: 2018-06-19 12:29:05
  • Modify Date: 2024-01-12 10:25:03
  • (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research[1].

Name (±)-Lisofylline
Synonyms R-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine
(R)-3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione
1-[(5R)-5-Hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Penthydroxifillyne
HYDROXY PENTOXIFYLLINE
Lisofylline
1-(5-Hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-
UNII:R99EE080JS
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-
ProTec
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-, (R)-
1-[(R)-5-Hydroxyhexyl]theobromine
CT 1501R
Description (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research[1].
Related Catalog
References

[1]. Yang Z, et al. Lisofylline: a potential lead for the treatment of diabetes. Biochem Pharmacol. 2005 Jan 1;69(1):1-5.

Density 1.3±0.1 g/cm3
Boiling Point 511.2±56.0 °C at 760 mmHg
Melting Point 123-125ºC
Molecular Formula C13H20N4O3
Molecular Weight 280.323
Flash Point 263.0±31.8 °C
Exact Mass 280.153534
PSA 82.05000
LogP 0.34
Appearance solid | white
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.621
Storage condition Refrigerator
Water Solubility DMSO: soluble
RIDADR NONH for all modes of transport
WGK Germany 3

~91%

6493-06-7 structure

6493-06-7

Literature: Kala, Elzbieta P.; Wojcik, Tomasz Acta Poloniae Pharmaceutica - Drug Research, 2007 , vol. 64, # 2 p. 109 - 113
Precursor  1

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