116653-28-2

116653-28-2 structure

Name: Busulfan-D8
Chemical Name: (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate
CAS Number: 116653-28-2
Molecular Formula: C₆H₆D₈O₆S₂
Molecular Weight: 254.351
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-02-17 08:00:00
Modify Date: 2025-08-25 18:54:11
Busulfan-D8 is a deuterium labeled Busulfan. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. Busulfan forms both intra- and interstrand crosslinks on DNA. In mammals, Busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.

Name	(1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate
Synonyms	(H)Butane-1,4-diyl dimethanesulfonate Busulfan-d8 1,4-Butane-d-diol, dimethanesulfonate Myleran-d8 Busulphan-d8 d8-butane-1,4-diol-1,4-dimethane sulfonate Misulban-d8 GT-41-d8 1,4-Butanediol-d8-dimethanesulfonate Esters (H)-1,4-Butanediyl dimethanesulfonate Busulfex-d8 CB-2041-d8 d8-butane-1,4-dimesylate

Description	Busulfan-D8 is a deuterium labeled Busulfan. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. Busulfan forms both intra- and interstrand crosslinks on DNA. In mammals, Busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

124-63-0

74829-49-5

~99%

116653-28-2

Literature: Nezbedova, Lenka; Drandarov, Konstantin; Werner, Christa; Hesse, Manfred Helvetica Chimica Acta, 2000 , vol. 83, # 11 p. 2953 - 2960

Precursor 2
124-63-0 74829-49-5
DownStream 0