120068-36-2

120068-36-2 structure

Name: FIPRONIL-SULFONE
Chemical Name: fipronil-sulfone
CAS Number: 120068-36-2
Molecular Formula: C₁₂H₄Cl₂F₆N₄O₂S
Molecular Weight: 453.147
Catalog: Chemical pesticide Insecticide Organochlorine insecticide
Create Date: 2018-02-18 08:00:00
Modify Date: 2024-01-02 18:29:19
Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).

Name	fipronil-sulfone
Synonyms	1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]- 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulphonyl]-1H-pyrazole-3-carbonitrile Fipronil sulfone FIPRONIL-SULFONE T5NNJ AR BG FG DXFFF& CCN DSWXFFF EZ 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfonyl)pyrazole-3-carbonitrile

Description	Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. D Hainzl,et al. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chem Res Toxicol . 1998 Dec;11(12):1529-35.

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H400
Precautionary Statements	P273-P301 + P310
Hazard Codes	T,N
Risk Phrases	25-50
Safety Phrases	45-61
RIDADR	UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
RTECS	UQ3515375