120068-37-3

120068-37-3 structure

Name: Fipronil
Chemical Name: fipronil
CAS Number: 120068-37-3
Molecular Formula: C₁₂H₄Cl₂F₆N₄OS
Molecular Weight: 437.148
Catalog: Chemical pesticide Insecticide Organochlorine insecticide
Create Date: 2018-02-04 08:00:00
Modify Date: 2024-01-02 07:27:33
Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.

Name	fipronil
Synonyms	Fipronil (JAN) 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carbonitrile Fluocyanobenpyrazole EINECS 424-610-5 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile 1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]- 5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfinylpyrazole (±)-Fipronil 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)sulfinyl-1H-pyrazole-3-carbonitrile (±)-5-Amino-1-(2,6-dichloro-a,a,a-trifluoro-p-tolyl)-4-trifluoromethylsulfinylpyrazole-3-carbonitrile RM 1601 MFCD00867812 Termidor T5NNJ AR BG FG DXFFF& CCN DSO&XFFF EZ &&(RS) Form 5-Amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-[(trifluoromethyl)sulfinyl]pyrazole-3-carbonitrile Fipronil

Description	Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301 + H311 + H331-H319-H372-H410
Precautionary Statements	P261-P273-P280-P301 + P310 + P330-P302 + P352 + P312-P304 + P340 + P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	N: Dangerous for the environment;T: Toxic;
Risk Phrases	R23/24/25
Safety Phrases	S26-S36/37/39-S45-S60-S61
RIDADR	2588
WGK Germany	3.0
RTECS	UQ4430250
Packaging Group	III
Hazard Class	6.1(b)