FIPRONIL-SULFONE
FIPRONIL-SULFONE structure
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Common Name | FIPRONIL-SULFONE | ||
|---|---|---|---|---|
| CAS Number | 120068-36-2 | Molecular Weight | 453.147 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 531.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C12H4Cl2F6N4O2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 275.3±30.1 °C | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
Use of FIPRONIL-SULFONEFipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site). |
| Name | fipronil-sulfone |
|---|---|
| Synonym | More Synonyms |
| Description | Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site). |
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| Related Catalog | |
| References |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.6±50.0 °C at 760 mmHg |
| Molecular Formula | C12H4Cl2F6N4O2S |
| Molecular Weight | 453.147 |
| Flash Point | 275.3±30.1 °C |
| Exact Mass | 451.933624 |
| PSA | 110.15000 |
| LogP | 7.44 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.592 |
| Symbol |
GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H400 |
| Precautionary Statements | P273-P301 + P310 |
| Hazard Codes | T,N |
| Risk Phrases | 25-50 |
| Safety Phrases | 45-61 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all |
| RTECS | UQ3515375 |
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FIPRONIL-SULFONE CAS#:120068-36-2 |
| Literature: Tang, Ri-Yuan; Zhong, Ping; Lin, Qiu-Lian Journal of Fluorine Chemistry, 2006 , vol. 127, # 7 p. 948 - 953 |
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FIPRONIL-SULFONE CAS#:120068-36-2 |
| Literature: Chemical Research in Toxicology, , vol. 11, # 12 p. 1529 - 1535 |
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FIPRONIL-SULFONE CAS#:120068-36-2 |
| Literature: US2005/234119 A1, ; Page/Page column 27 ; |
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FIPRONIL-SULFONE CAS#:120068-36-2 |
| Literature: Chemical Research in Toxicology, , vol. 11, # 12 p. 1529 - 1535 |
| Precursor 2 | |
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| DownStream 0 | |
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Persistence and effect of processing on reduction of fipronil and its metabolites in chilli pepper (Capsicum annum L.) fruits.
Environ. Monit. Assess. 186(9) , 5429-37, (2014) A single laboratory UPLC-MS/MS method was developed and validated for the estimation of fipronil and its metabolites in fresh and dry chilli pepper fruits. Dissipation of fipronil on chilli fruits was... |
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Fipronil sulfone induced higher cytotoxicity than fipronil in SH-SY5Y cells: Protection by antioxidants.
Toxicol. Lett. 252 , 42-9, (2016) Fipronil is a broad spectrum insecticide from the phenyl pyrazole family, which targets GABA receptor. Limited information is available about the metabolite fipronil sulfone cytotoxic actions. This st... |
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DBS-platform for biomonitoring and toxicokinetics of toxicants: proof of concept using LC-MS/MS analysis of fipronil and its metabolites in blood.
Sci. Rep. 6 , 22447, (2016) A simple, sensitive and high throughput LC-MS/MS method was developed and validated for quantification of fipronil, fipronil sulfone and fipronil desulfinyl in rat and human dried blood spots (DBS). D... |
| 1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]- |
| 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile |
| 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulphonyl]-1H-pyrazole-3-carbonitrile |
| Fipronil sulfone |
| FIPRONIL-SULFONE |
| T5NNJ AR BG FG DXFFF& CCN DSWXFFF EZ |
| 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfonyl)pyrazole-3-carbonitrile |