1754-62-7
1754-62-7 structure
- Name: methyl (E)-cinnamate
- Chemical Name: methyl cinnamate
- CAS Number: 1754-62-7
- Molecular Formula: C10H10O2
- Molecular Weight: 162.18500
- Catalog: Flavors and spices Synthetic spice Carboxylic acid and ester perfume Aromatic carboxylic acid ester
- Create Date: 2018-05-07 08:00:00
- Modify Date: 2024-01-08 16:15:42
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Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1].
| Name | methyl cinnamate |
|---|---|
| Synonyms |
MFCD00008458
Methyl trans-cinnamate |
| Description | Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Methyl (E)-cinnamate (0~30 μM; 24 hours; MC3T3-E1 cells) significantly increases the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreases the expression levels of Survivin and Bcl-2, and significantly increases TUNEL-positive and DAPI-stained cells[1]. Methyl (E)-cinnamate (0~30 μM;7 days; MC3T3-E1 cells) suppresses the osteoblast differentiation[1]. Methyl (E)-cinnamate (1~100 μM; 24 and 48 hours; MC3T3-E1 cells) decreases cell survival and induces morphological changes. EMC decreases MAPKs signaling and cell migration[1]. Western Blot Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreased the expression levels of Survivin and Bcl-2. Apoptosis Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased TUNEL-positive and DAPI-stained cells. Cell Differentiation Assay[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 7 days Result: Suppressed the osteoblast differentiation. |
| References |
| Density | 1.078 g/cm3 |
|---|---|
| Boiling Point | 261.9ºC at 760 mmHg |
| Melting Point | 34-38ºC |
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.18500 |
| Flash Point | 141.3ºC |
| Exact Mass | 162.06800 |
| PSA | 26.30000 |
| LogP | 1.87280 |
| Vapour Pressure | 0.0112mmHg at 25°C |
| Index of Refraction | 1.558 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | GE0190000 |