methyl (E)-cinnamate
methyl (E)-cinnamate structure
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Common Name | methyl (E)-cinnamate | ||
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| CAS Number | 1754-62-7 | Molecular Weight | 162.18500 | |
| Density | 1.078 g/cm3 | Boiling Point | 261.9ºC at 760 mmHg | |
| Molecular Formula | C10H10O2 | Melting Point | 34-38ºC | |
| MSDS | Chinese USA | Flash Point | 141.3ºC | |
Use of methyl (E)-cinnamateMethyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1]. |
| Name | methyl cinnamate |
|---|---|
| Synonym | More Synonyms |
| Description | Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1]. |
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| Related Catalog | |
| In Vitro | Methyl (E)-cinnamate (0~30 μM; 24 hours; MC3T3-E1 cells) significantly increases the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreases the expression levels of Survivin and Bcl-2, and significantly increases TUNEL-positive and DAPI-stained cells[1]. Methyl (E)-cinnamate (0~30 μM;7 days; MC3T3-E1 cells) suppresses the osteoblast differentiation[1]. Methyl (E)-cinnamate (1~100 μM; 24 and 48 hours; MC3T3-E1 cells) decreases cell survival and induces morphological changes. EMC decreases MAPKs signaling and cell migration[1]. Western Blot Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreased the expression levels of Survivin and Bcl-2. Apoptosis Analysis[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 24 hours Result: Significantly increased TUNEL-positive and DAPI-stained cells. Cell Differentiation Assay[1] Cell Line: MC3T3-E1 cells Concentration: 0~30 μM Incubation Time: 7 days Result: Suppressed the osteoblast differentiation. |
| References |
| Density | 1.078 g/cm3 |
|---|---|
| Boiling Point | 261.9ºC at 760 mmHg |
| Melting Point | 34-38ºC |
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.18500 |
| Flash Point | 141.3ºC |
| Exact Mass | 162.06800 |
| PSA | 26.30000 |
| LogP | 1.87280 |
| Vapour Pressure | 0.0112mmHg at 25°C |
| Index of Refraction | 1.558 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | GE0190000 |
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Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage.
Bioorg. Med. Chem. 19 , 2392-6, (2011) In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic a... |
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BF3·OEt2-promoted diastereoselective diacetoxylation of alkenes by PhI(OAc)2.
J. Org. Chem. 76(24) , 9997-10004, (2011) Selective syn and anti diacetoxylations of alkenes have been achieved using a PhI(OAc)(2)/BF(3)·OEt(2) system in the presence and absence of water, respectively. A broad range of substrates including ... |
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Stoichiometric model of alpha-cyclodextrin complex formation.
J. Pharm. Sci. 69(5) , 564-7, (1980) The solubility, spectral, and kinetic methods were used to study complexing between alpha-cyclodextrin (ligand, L) and 3,5-dimethoxycinnamic acid, benzalacetone, and methyl cinnamate (substrates, S). ... |
| MFCD00008458 |
| Methyl trans-cinnamate |