Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Brompheniramine hydrogen maleate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

980-71-2

980-71-2 structure

Name: Brompheniramine Maleate
Chemical Name: brompheniramine maleate
CAS Number: 980-71-2
Molecular Formula: C₂₀H₂₃BrN₂O₄
Molecular Weight: 435.312
Catalog: API Antiallergic Antihistamine
Create Date: 2018-09-16 17:56:28
Modify Date: 2026-07-07 16:37:07
Brompheniramine maleate is a histamine H1 receptors antagonist.Target: Histamine H1 ReceptorBrompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis. It is a first-generation antihistamine. Brompheniramine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, Arvid Carlsson and his colleagues, working at the Swedish company Astra AB, were able to derive the first marketed selective serotonin reuptake inhibitor, zimelidine, from brompheniramine. Brompheniramine had a long half-life and large volume of distribution in normal adults. It also had a prolonged antihistaminic effect in the skin as evidenced by suppression of the wheal and flare response to histamine and by suppression of pruritus [1, 2].

Name	brompheniramine maleate
Synonyms	Brompheniramine Maleate 1.0 mg/ml in Methanol (as free base) 2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-pyridinmaleate(1:1) Brompheniramine MaL BroMpheniraMine hydr Brompheniramine d BROMPHENIRAMINE MALEATE SALT 2-pyridinepropanamine, g-(4-bromophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1) BROMOPHENIRAMINE MALEATE pabromdylaminemaleate acide (2Z)-but-2-ènedioïque - 3-(4-bromophényl)-N,N-diméthyl-3-pyridin-2-ylpropan-1-amine (1:1) 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate dimegan γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinropanamine,(2Z)-2-butenedioate (1:1) (±)-2-[p-Bromo-a-(2-dimethylaminoethyl)benzyl]pyridine Maleate dl-Bromopheniramine Maleate (±)-Brompheniramine maleate Brompheniramine maleate CRS BROMPHENIRAMINEMALEATE Brompheniramine maleate in methanol g-(4-bromophenyl)-N,N-dimethyl-2-pyridinropanaminemaleate BROMPHENIRAMINE MALEATE, PHMA Brompheniramine hydrogen maleate //BP 1-(n,n-dimethylamino)-3-(p-bromophenyl)-3-(alpha-pyridyl)propane maleate Brompheniramine maleate solution EINECS 213-562-9 brompheniramine hydrogen maleate 2-Pyridinepropanamine, γ-(4-bromophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1) Bromopheniramine Maleate Salt Rolabromophen (±)-Brompheniramine maleate salt RS-brompheniramine maleate 3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate (2Z)-But-2-endisäure--3-(4-bromphenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amin(1:1) β-Phenyl-γ-aminobutyric acid gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinropanamin(z)-butenedioate 3-(4-Bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine (2Z)-2-butenedioate (1:1) Brompheniramine maleate, 10 mM in DMSO 2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate(1:1) (+/-)-1-(4-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane C10781600 (±)-BrompheniraminEmaleate (+/-)-BROMPHENIRAMINE MALEATE SALT Ilvin Maleate pabromodylaminemaleate (RS)-brompheniramine γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinropanaminemaleate gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinropanamin(z)-2-butenedioate brompheniramine (maleate) N-(3-THIOXO-3H-1,2,4-DITHIAZOL-5-YL)-2-THIOPHENECARBOXAMIDE D-Brompheniramine γ-(4-BroMophenyl)-N,N-diMethyl TIANFU-CHEM -2 Brompheniramine hydrogen maleate dimetane Brompheniramine maleateQ: What is Brompheniramine maleate Q: What is the CAS Number of Brompheniramine maleate Q: What is the storage condition of Brompheniramine maleate Q: What e the applications of Brompheniramine maleate dimetanemaleate 3-(4-Bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine (2Z)-but-2-enedioate (1:1) 1-p-bromophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate MFCD00057367 PARABROMODYLAMINE MALEATE Brompheniramine maleate 100 μg/ml Methanol BROMPHENIRAMINE MALEATE dimotane ilvinmaleate

Description	Brompheniramine maleate is a histamine H1 receptors antagonist.Target: Histamine H1 ReceptorBrompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis. It is a first-generation antihistamine. Brompheniramine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, Arvid Carlsson and his colleagues, working at the Swedish company Astra AB, were able to derive the first marketed selective serotonin reuptake inhibitor, zimelidine, from brompheniramine. Brompheniramine had a long half-life and large volume of distribution in normal adults. It also had a prolonged antihistaminic effect in the skin as evidenced by suppression of the wheal and flare response to histamine and by suppression of pruritus [1, 2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology
References	[1]. http://en.wikipedia.org/wiki/Brompheniramine [2]. Simons, F.E., E.M. Frith, and K.J. Simons, The pharmacokinetics and antihistaminic effects of brompheniramine. J Allergy Clin Immunol, 1982. 70(6): p. 458-64.

Boiling Point	403ºC at 760 mmHg
Melting Point	134-135ºC
Molecular Formula	C₂₀H₂₃BrN₂O₄
Molecular Weight	435.312
Exact Mass	434.084106
PSA	90.73000
LogP	3.63950

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US4025000

CAS REGISTRY NUMBER :: 980-71-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C16-H19-Br-N2.C4-H4-O4

MOLECULAR WEIGHT :: 435.36

WISWESSER LINE NOTATION :: T6NJ BYR DE&2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 318 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,19,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 76 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,19,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84807 No. of Facilities: 967 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 3990 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84807 No. of Facilities: 314 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 6708 (estimated) No. of Female Employees: 3572 (estimated)

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Hazard Codes	Xi
Risk Phrases	R22
Safety Phrases	S36
RIDADR	UN 3249
WGK Germany	3
RTECS	US4025000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2934999090
Flash Point(F)	48.2 °F
Flash Point(C)	9 °C

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

2415500-35-3	2415583-11-6
2415628-75-8	2415532-94-2
2415620-49-2	2415603-72-2
2415562-08-0	2415501-25-4
2415569-65-0	2415509-94-1