185629-22-5

185629-22-5 structure

Name: BMS 961
Chemical Name: 3-Fluoro-4-{[hydroxy(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-nap hthalenyl)acetyl]amino}benzoic acid
CAS Number: 185629-22-5
Molecular Formula: C₂₃H₂₆FNO₄
Molecular Weight: 399.45500
Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
Create Date: 2016-02-12 02:15:52
Modify Date: 2024-01-05 15:57:37
BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity[1].

Name	3-Fluoro-4-{[hydroxy(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-nap hthalenyl)acetyl]amino}benzoic acid

Description	BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR
Target	RARγ
In Vitro	BMS961 inhibits the expression of Dectin-1 and pro-inflammatory cytokines[1].
References	[1]. Wang XC, et al. Effects of retinoic acid receptor-γ on the Aspergillus fumigatus induced innate immunity response in human corneal epithelial cells. Int J Ophthalmol. 2016 Dec 18;9(12):1713-1718.