BMS 961

Modify Date: 2024-01-05 15:57:37

BMS 961 Structure
BMS 961 structure
Common Name BMS 961
CAS Number 185629-22-5 Molecular Weight 399.45500
Density N/A Boiling Point N/A
Molecular Formula C23H26FNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS 961


BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity[1].

 Names

Name 3-Fluoro-4-{[hydroxy(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-nap hthalenyl)acetyl]amino}benzoic acid

 BMS 961 Biological Activity

Description BMS961 is a selective retinoic acid receptor-γ (RARγ) agonist. BMS961 shows anti-inflammatory activity[1].
Related Catalog
Target

RARγ

In Vitro BMS961 inhibits the expression of Dectin-1 and pro-inflammatory cytokines[1].
References

[1]. Wang XC, et al. Effects of retinoic acid receptor-γ on the Aspergillus fumigatus induced innate immunity response in human corneal epithelial cells. Int J Ophthalmol. 2016 Dec 18;9(12):1713-1718.

 Chemical & Physical Properties

Molecular Formula C23H26FNO4
Molecular Weight 399.45500
Exact Mass 399.18500
PSA 90.12000
LogP 5.19450
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