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132185-83-2

132185-83-2 structure
132185-83-2 structure
  • Name: 5alpha-Hydroxycostic acid
  • Chemical Name: 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
  • CAS Number: 132185-83-2
  • Molecular Formula: C15H22O3
  • Molecular Weight: 250.333
  • Catalog: Natural product Sesquiter
  • Create Date: 2017-05-07 07:24:35
  • Modify Date: 2024-01-01 17:59:36
  • 5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].

Name 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
Synonyms 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aR)-
Description 5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].
Related Catalog
References

[1]. Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222.

Density 1.1±0.1 g/cm3
Boiling Point 406.4±38.0 °C at 760 mmHg
Molecular Formula C15H22O3
Molecular Weight 250.333
Flash Point 213.8±23.3 °C
Exact Mass 250.156891
PSA 57.53000
LogP 3.19
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.540
Hazard Codes Xi