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357645-16-0

357645-16-0 structure
357645-16-0 structure
  • Name: 7,8,9,9-Tetradehydroisolariciresinol
  • Chemical Name: 7,8,9,9-Tetradehydroisolariciresinol
  • CAS Number: 357645-16-0
  • Molecular Formula: C20H20O6
  • Molecular Weight: 356.369
  • Catalog: Natural product Lignans
  • Create Date: 2017-04-08 07:58:23
  • Modify Date: 2024-01-04 10:26:58
  • Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1].

Name 7,8,9,9-Tetradehydroisolariciresinol
Synonyms 2-Naphthalenecarboxaldehyde, 3,4-dihydro-6-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-, (3R,4S)-
(3R,4S)-6-Hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-3,4-dihydro-2-naphthalenecarbaldehyde
Description Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1].
Related Catalog
References

[1]. Zhou Y, et al. Vitexins, nature-derived lignan compounds, induce apoptosis and suppress tumor growth. Clin Cancer Res. 2009 Aug 15;15(16):5161-9.  

Density 1.4±0.1 g/cm3
Boiling Point 587.4±50.0 °C at 760 mmHg
Molecular Formula C20H20O6
Molecular Weight 356.369
Flash Point 211.0±23.6 °C
Exact Mass 356.125977
PSA 96.22000
LogP 2.59
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.664
Hazard Codes Xi