Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pravastatin sodium
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

81131-70-6

81131-70-6 structure

Name: Pravastatin (sodium)
Chemical Name: pravastatin sodium
CAS Number: 81131-70-6
Molecular Formula: C₂₃H₃₅NaO₇
Molecular Weight: 446.51
Catalog: API Circulatory system medication Regulating blood lipids
Create Date: 2018-04-14 08:00:00
Modify Date: 2026-07-07 22:38:44
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.Target: HMG-CoA reductasePravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.Pravastatin is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is recommended to be used only after other measures such as diet, exercise, and weight reduction have not improved cholesterol levels.The evidence for the use of pravastatin is generally weaker than for other statins. The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT), failed to demonstrate a difference in all-cause mortality or nonfatal myocardial infarction/fatal coronary heart disease rates between patients receiving pravastatin 40mg daily (a common starting dose) and those receiving usual care.

Name	pravastatin sodium
Synonyms	Selipran PRAVACHOL 1-Naphthalenehtanoicacid Oliprevin Sodium (+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoate Sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate Pravastatin sodium a HMG-CoA reductase inhibitor 2-alpha,6-alpha,8-beta(r),8a-alpha)) Pravastatin sodium PRAVASTATIN SODIUM SALT (BET, DELT,1S,2S,6S,8S,8-1,2,6,7,8,8A-HEXAHYDRO-BETA, DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHTANOIC ACID SODIUM (BETA R,DELTA R,1S,2S,6S,8S,8-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-1-NAPHTHALENEHTANOIC ACID MONOSODIUM SALT PRAVASTATIN SODIUM Lipidal Pravastatine Pravastatin, Sodium Salt - - Calbiochem 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt, (βR,δR,1S,2S,6S,8S,8aR)- (1:1) 1-Naphthalenehtanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (bR,dR,1S,2S,6S,8S,8)- (9CI) tastatin sodium salt hydrate utoxy)-beta,delta,6-trihydroxy-,monosodiumsalt,(1s-(1-alpha(beta-s,delta-s MFCD00887601 3BETA-HYDROXYCOMPACTIN, NA tastatin sodium salt, (βR, δR,1S,2S,6S,8S,8-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthalenehtanoic acid sodium 1-Naphthalenehtanoic acid, 1,2,6,7,8,8a-hexahydro-.beta.,.delta.,6-trihydroxy-2-methyl-8-(2S)-2-methyl-1-oxobutoxy-, monosodium salt, (.beta.R,.delta.R,1S,2S,6S,8S,8) Liprevil 3b-Hydroxycompactin Sodium Salt (βR, δR,1S,2S,6S,8S,8-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthalenehtanoic acid sodium hydrate TASTATIN SODIUM tastatin Pravasin Pravasine [1S-[1a(bS,dS),2a,6a,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt ELISOR Pravastatinesodium KOPOSTAT Pravacol Pravastatinsodium,(S) Elisor, Kopostat, Mevalotin, Pravachol, Pravaselect Pavastatin PravastatinNaC23H35Na07 Natrium-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoat Mevalotin, CS 514, SQ Pravastatin sodium, >= lipostat (R,dR,1S,2S,6S,8S,8-1,2,6,7,8,8a-Hexahydro-,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthalenehtanoic Acid Sodium Salt sq31000 Selektine Sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthalenyl]heptanoate Vasten [1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthalenehtanoic acid monosodium salt sodiuM (3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8-6-hydroxy-2-Methyl-8-(((S)-2-Methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)htanoate (βr, δr,1s,2s,6s,8s,8-1,2,6,7,8,8a-hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2s)-2-methyl-1-oxobutoxyl]-1-naphthalenehtanoic acid sodium (3R,5R)-7-((1S,2S,6S,8S,8-2,6-dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyhtanoate [1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-tri astatinsodium (BETA-R,DELTA-R,1S,2S,6S,8S,8-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHTANOIC ACID NA PRAVASELECT Secobbital Solution, 100ppm MEVALOTIN 3b-Hydroxycompactin sodium salt PRAVASTATIN (SODIUM) (CS-514 (SODIUM)) Prava Pravastatin sodiuM salt hydrate 1-Naphthalenehtanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1a(bS,dS),2a,6a,8b(R),8aa]]

Description	Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.Target: HMG-CoA reductasePravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.Pravastatin is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is recommended to be used only after other measures such as diet, exercise, and weight reduction have not improved cholesterol levels.The evidence for the use of pravastatin is generally weaker than for other statins. The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT), failed to demonstrate a difference in all-cause mortality or nonfatal myocardial infarction/fatal coronary heart disease rates between patients receiving pravastatin 40mg daily (a common starting dose) and those receiving usual care.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Research Areas >> Cardiovascular Disease
References	[1]. McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.

Boiling Point	634.5ºCat 760 mmHg
Melting Point	171.2-173 °C
Molecular Formula	C₂₃H₃₅NaO₇
Molecular Weight	446.51
Flash Point	213.2ºC
PSA	124.29000
LogP	2.44040
Storage condition	2-8°C
Water Solubility	H2O: 19 mg/mL

Hazard Codes	F: Flammable;C: Corrosive;
Risk Phrases	R11
Safety Phrases	16-26-36/37/39-45
RIDADR	3077
WGK Germany	2
RTECS	QJ7185000
Packaging Group	III
Hazard Class	9
HS Code	2932999099

81093-37-0

~87%

81131-70-6

Literature: BIOCON LIMITED Patent: WO2005/19155 A1, 2005 ; Location in patent: Page/Page column 8 ;

73573-88-3

81131-70-6

Literature: US2005/113446 A1, ; Page/Page column 6 ;

Precursor 2
81093-37-0 73573-88-3
DownStream 1
81093-37-0

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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