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DC Chemicals Limited
China
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Dayang Chem (Hangzhou) Co., Ltd.
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Zhejiang Hangyu API Co., Ltd
China
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Henan Tianfu Chemical Co., Ltd.
China
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2624-44-4

2624-44-4 structure

2624-44-4 structure

Name: Etamsylate
Chemical Name: 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1)
CAS Number: 2624-44-4
Molecular Formula: C₁₀H₁₇NO₅S
Molecular Weight: 263.311
Catalog: API Blood system medication Hemostatic drug
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-01 22:19:48
Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.

Name	2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1)
Synonyms	Diethylamine 2,5-Dihydroxybenzenesulfonate 1-Hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonic Acid Compd with Diethylamine 2,5-Dihydroxybenzenesulfonic acid - N-ethylethanamine (1:1) MFCD00867499 Etamsylate EINECS 220-090-7 Ethamsylate 2,5-Dihydroxybenzenesulfonic Acid Compd with N-Ethylethanamine Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1) Benzenesulfonic acid,2,5-dihydroxy-,compd. with N-ethylethanamine

Description	Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Cardiovascular Disease

Boiling Point	496.4ºC at 760 mmHg
Melting Point	127-131ºC
Molecular Formula	C₁₀H₁₇NO₅S
Molecular Weight	263.311
Flash Point	254ºC
Exact Mass	263.082733
PSA	115.24000
LogP	2.43200
Vapour Pressure	1.13E-10mmHg at 25°C
Storage condition	2~8 ℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB6145000

CHEMICAL NAME :: Benzenesulfonic acid, 2,5-dihydroxy-, compd. with diethylamine

CAS REGISTRY NUMBER :: 2624-44-4

LAST UPDATED :: 199806

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C6-H6-O5-S.C4-H11-N

MOLECULAR WEIGHT :: 263.34

WISWESSER LINE NOTATION :: WSQR BQ EQ &2M2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29750 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - excitement

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6040 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - excitement

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Mold - Aspergillus nidulans

DOSE/DURATION :: 1 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974

Hazard Codes	Xi
HS Code	2921199090

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%