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306-23-0

306-23-0 structure
306-23-0 structure
  • Name: Hydroxyphenyllactic acid
  • Chemical Name: 3-(4-hydroxyphenyl)lactic acid
  • CAS Number: 306-23-0
  • Molecular Formula: C9H10O4
  • Molecular Weight: 182.173
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2018-09-18 20:55:46
  • Modify Date: 2024-01-03 09:39:09
  • Hydroxyphenyllactic acid is an antifungal metabolite.

Name 3-(4-hydroxyphenyl)lactic acid
Synonyms p-Hydroxyphenyl lactic acid
2-Hydroperoxy-2-phenylpropanoic acid
dl-p-Hydroxyphenyllactic acid
DL-4-Hydroxyphenyllactic Acid
3-(p-hydroxyphenyl)-D,L-lactic acid
4-Hydroxyphenyllactic acid
3-(4-hydroxyphenyl)-lactic acid
Benzeneacetic acid, α-hydroperoxy-α-methyl-
3-(4'-Hydroxyphenyl)-2-hydroxypropanoic acid
HPLA
2-Hydroxy-3-(p-hydroxyphenyl)propionic acid
2-hydroxy-3-(4-hydroxyphenyl)propanoic acid
Description Hydroxyphenyllactic acid is an antifungal metabolite.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Hydroxyphenyllactic acid (4-hydroxyphenyllactic acid) is an antifungal metabolite[1].
References

[1]. Mu W, et al. Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation. J Biosci Bioeng. 2010 Apr;109(4):369-71.

Density 1.3±0.1 g/cm3
Boiling Point 370.0±35.0 °C at 760 mmHg
Molecular Formula C9H10O4
Molecular Weight 182.173
Flash Point 152.5±19.4 °C
Exact Mass 182.057907
PSA 77.76000
LogP 2.13
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.563

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OD5500000
CHEMICAL NAME :
Lactic acid, 3-(p-hydroxyphenyl)-
CAS REGISTRY NUMBER :
306-23-0
LAST UPDATED :
199803
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H10-O4
MOLECULAR WEIGHT :
182.19
WISWESSER LINE NOTATION :
QVY1&OR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg female 15-21 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Lungs, Thorax, or Respiration - tumors
REFERENCE :
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg female 15-21 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Blood - tumors
REFERENCE :
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
REFERENCE :
VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2800 mg/kg/10W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - leukemia
REFERENCE :
GETRE8 Gematologiya i Transfuziologiya. Hematology and Transfusion Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.28- 1983- Volume(issue)/page/year: 28(2),50,1983
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
HS Code 2918290000
HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%