CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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OD5500000
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CHEMICAL NAME :
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Lactic acid, 3-(p-hydroxyphenyl)-
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CAS REGISTRY NUMBER :
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306-23-0
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LAST UPDATED :
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199803
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C9-H10-O4
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MOLECULAR WEIGHT :
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182.19
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WISWESSER LINE NOTATION :
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QVY1&OR DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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800 mg/kg female 15-21 day(s) after conception
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Lungs, Thorax, or Respiration - tumors
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REFERENCE :
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BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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800 mg/kg female 15-21 day(s) after conception
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Blood - tumors
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REFERENCE :
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BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1600 mg/kg/8W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
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REFERENCE :
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VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2800 mg/kg/10W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - leukemia
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REFERENCE :
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GETRE8 Gematologiya i Transfuziologiya. Hematology and Transfusion Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.28- 1983- Volume(issue)/page/year: 28(2),50,1983
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