Top Suppliers:I want be here


181769-57-3

181769-57-3 structure
181769-57-3 structure
  • Name: (Rac)-Calpain Inhibitor XII
  • Chemical Name: Calpain Inhibitor XII
  • CAS Number: 181769-57-3
  • Molecular Formula: C26H34N4O5
  • Molecular Weight: 482.572
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
  • Create Date: 2017-09-09 17:34:45
  • Modify Date: 2024-01-11 08:51:25
  • (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

Name Calpain Inhibitor XII
Synonyms N-[(benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(pyridin-2-ylmethyl)amino]hexan-3-yl}leucinamide
N-[(Benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(2-pyridinylmethyl)amino]-3-hexanyl}leucinamide
Carbamic acid, N-[1-[[[1-[1,2-dioxo-2-[(2-pyridinylmethyl)amino]ethyl]butyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester
Description (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.
Related Catalog
Density 1.2±0.1 g/cm3
Molecular Formula C26H34N4O5
Molecular Weight 482.572
Exact Mass 482.252930
PSA 126.49000
LogP 3.17
Index of Refraction 1.548