(Rac)-Calpain Inhibitor XII structure
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Common Name | (Rac)-Calpain Inhibitor XII | ||
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CAS Number | 181769-57-3 | Molecular Weight | 482.572 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C26H34N4O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of (Rac)-Calpain Inhibitor XII(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. |
Name | Calpain Inhibitor XII |
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Synonym | More Synonyms |
Description | (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. |
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Related Catalog |
Density | 1.2±0.1 g/cm3 |
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Molecular Formula | C26H34N4O5 |
Molecular Weight | 482.572 |
Exact Mass | 482.252930 |
PSA | 126.49000 |
LogP | 3.17 |
Index of Refraction | 1.548 |
N-[(benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(pyridin-2-ylmethyl)amino]hexan-3-yl}leucinamide |
N-[(Benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(2-pyridinylmethyl)amino]-3-hexanyl}leucinamide |
Carbamic acid, N-[1-[[[1-[1,2-dioxo-2-[(2-pyridinylmethyl)amino]ethyl]butyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester |