(Rac)-Calpain Inhibitor XII
Modify Date: 2025-08-25 09:14:58
(Rac)-Calpain Inhibitor XII structure
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Common Name | (Rac)-Calpain Inhibitor XII | ||
|---|---|---|---|---|
| CAS Number | 181769-57-3 | Molecular Weight | 482.572 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C26H34N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (Rac)-Calpain Inhibitor XII(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. |
| Name | Calpain Inhibitor XII |
|---|---|
| Synonym | More Synonyms |
| Description | (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. |
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| Related Catalog |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H34N4O5 |
| Molecular Weight | 482.572 |
| Exact Mass | 482.252930 |
| PSA | 126.49000 |
| LogP | 3.17 |
| Index of Refraction | 1.548 |
| N-[(benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(pyridin-2-ylmethyl)amino]hexan-3-yl}leucinamide |
| N-[(Benzyloxy)carbonyl]-N-{1,2-dioxo-1-[(2-pyridinylmethyl)amino]-3-hexanyl}leucinamide |
| Carbamic acid, N-[1-[[[1-[1,2-dioxo-2-[(2-pyridinylmethyl)amino]ethyl]butyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester |