142628-53-3

142628-53-3 structure

Name: macrocarpal C
Chemical Name: 5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde
CAS Number: 142628-53-3
Molecular Formula: C₂₈H₃₈O₅
Molecular Weight: 454.60
Catalog: Natural product Sesquiter
Create Date: 2017-07-30 09:16:13
Modify Date: 2024-01-19 18:09:12
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

Name	5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde
Synonyms	2,4,6-Trihydroxy-5-{3-methyl-1-[(1aS,4aR,7R,7aS,7bS)-1a,7,7b-trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-yl]butyl}isophthalaldehyde 1,3-Benzenedicarboxaldehyde, 5-[1-[(1aS,4aR,7R,7aS,7bS)-decahydro-1a,7,7b-trimethyl-4-methylene-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy- 2,4,6-Trihydroxy-5-{(1R)-3-methyl-1-[(1aR,4aR,7S,7aR,7bR)-1,1,7-trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-yl]butyl}isophthalaldehyde 1,3-Benzenedicarboxaldehyde, 5-[(1R)-1-[(1aR,4aR,7S,7aR,7bR)-decahydro-1,1,7-trimethyl-4-methylene-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy- macrocarpal-C macrocarpal G macrocarpal C

Description	Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Jack Ho Wong, et al. Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes. Chin Med. 2015, 10, 34.

Hazard Codes	Xi