133699-09-9

133699-09-9 structure

Name: Tr-PEG3-OH
Chemical Name: 2-[2-(2-trityloxyethoxy)ethoxy]ethanol
CAS Number: 133699-09-9
Molecular Formula: C₂₅H₂₈O₄
Molecular Weight: 392.48700
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-01-15 11:54:46
Modify Date: 2024-01-12 12:23:54
Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name	2-[2-(2-trityloxyethoxy)ethoxy]ethanol
Synonyms	Ethanol,2-[2-[2-(triphenylmethoxy)ethoxy]ethoxy] Tr-PEG4 1-hydroxy-8-trityloxy-3,6-dioxaoctane 10,10,10-triphenyl-3,6,9-trioxadecan-1-ol 2-(2-(2-(trityloxy)ethoxy)ethoxy)ethanol triethylene glycol monotrityl ether 8-(triphenylmethyloxy)-3,6-dioxaoctan-1-ol 10,10,10-Triphenyl-3,6,9-trioxadecanol

Description	Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Chou CH, et al. Glycan-Directed Grafting-from Polymerization of Immunoglobulin G: Site-Selectively Modified IgG-Polymer Conjugates with Preserved Biological Activity. Biomacromolecules. 2018 Jul 9;19(7):3086-3095.