Lenalidomide-5-Br

Modify Date: 2024-01-06 18:58:10

Lenalidomide-5-Br structure	Common Name	Lenalidomide-5-Br
	CAS Number	1010100-26-1	Molecular Weight	323.14
	Density	1.688±0.06 g/cm3	Boiling Point	587.6±50.0 °C
	Molecular Formula	C₁₃H₁₁BrN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lenalidomide-5-Br

Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC[1].

Name	Lenalidomide-5-Br
Synonym	More Synonyms

Description	Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density	1.688±0.06 g/cm3
Boiling Point	587.6±50.0 °C
Molecular Formula	C₁₃H₁₁BrN₂O₃
Molecular Weight	323.14

3-(5-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

DC Chemicals Limited
China
Product Name: Lenalidomide-5-Br
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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Lenalidomide-5-Br

Use of Lenalidomide-5-Br

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