CP-66948
Modify Date: 2024-01-02 15:22:48
CP-66948 structure
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Common Name | CP-66948 | ||
|---|---|---|---|---|
| CAS Number | 101189-47-3 | Molecular Weight | 292.40300 | |
| Density | 1.34g/cm3 | Boiling Point | 561.6ºC at 760mmHg | |
| Molecular Formula | C13H20N6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 293.4ºC | |
Use of CP-66948CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties. |
| Name | 1-[4-(2-methyl-1H-imidazol-5-yl)-1,3-thiazol-2-yl]-2-pentylguanidine |
|---|---|
| Synonym | More Synonyms |
| Description | CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties. |
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| Related Catalog | |
| In Vivo | The affinity of CP-66,948 for the guinea pig atria histamine H2-receptor is 15 times greater than that of cimetidine and seven times greater than that of ranitidine. In vivo, the ED50 value for inhibition of gastric acid secretion in pylorus-ligated rats is 2 mg/kg intraduodenally, and in histamine or pentagastrin-stimulated Heidenhain pouch dogs the antisecretory ED50 values are 0.3 mg/kg per os and 1.0 mg/kg per os, respectively. CP-66,948 also inhibits ethanol-induced gastric hemorrhagic lesions in rats following either oral or systemic administration (ED50 values of 12 mg/kg per os and 6 mg/kg subcutaneously)[1]. |
| References |
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 561.6ºC at 760mmHg |
| Molecular Formula | C13H20N6S |
| Molecular Weight | 292.40300 |
| Flash Point | 293.4ºC |
| Exact Mass | 292.14700 |
| PSA | 117.72000 |
| LogP | 3.53170 |
| Vapour Pressure | 1.22E-12mmHg at 25°C |
| Index of Refraction | 1.675 |
| Storage condition | 2-8℃ |
| 2-(N-Pentyl-N''-guanidino)-4-(2-methylimidazol-4-yl)thiazole |
| CP-66,948 |
| Guanidine,N-(4-(2-methyl-1H-imidazol-4-yl)-2-thiazolyl)-N'-pentyl |
| CP-66948 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: CP-66948?
- Price: Negotiable
- Purity: 99.14%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-(N-Pentyl-N'-guanidino)-4-(2-methylimidazol-4-yl)thiazole
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: $696/1mg
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