imidacloprid d4 (imidazolidin-4,4,5,5 d4)

Modify Date: 2024-01-11 18:44:00

imidacloprid d4 (imidazolidin-4,4,5,5 d4) Structure
imidacloprid d4 (imidazolidin-4,4,5,5 d4) structure
Common Name imidacloprid d4 (imidazolidin-4,4,5,5 d4)
CAS Number 1015855-75-0 Molecular Weight 259.686
Density 1.6±0.1 g/cm3 Boiling Point 442.3±55.0 °C at 760 mmHg
Molecular Formula C9H6ClD4N5O2 Melting Point N/A
MSDS Chinese USA Flash Point 221.3±31.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of imidacloprid d4 (imidazolidin-4,4,5,5 d4)


Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2].

 Names

Name N-[1-[(6-chloropyridin-3-yl)methyl]-4,4,5,5-tetradeuterioimidazol-2-yl]nitramide
Synonym More Synonyms

  Biological Activity

Description Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Kim J, et al. Imidacloprid, a neonicotinoid insecticide, induces insulin resistance. J Toxicol Sci. 2013;38(5):655-60.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 442.3±55.0 °C at 760 mmHg
Molecular Formula C9H6ClD4N5O2
Molecular Weight 259.686
Flash Point 221.3±31.5 °C
Exact Mass 259.077423
PSA 86.34000
LogP -0.43
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.706

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
RIDADR NONH for all modes of transport

 Articles4

More Articles
Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 969 , 85-94, (2014)

A rapid and sensitive analytical method was developed for simultaneous determination of eight neonicotinoid insecticides (acetamiprid, clothianidin, dinotefuran, flonicamid, imidacloprid, nitenpyram, ...

Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics.

PLoS ONE 11 , e0146335, (2016)

Neonicotinoids, which are novel pesticides, have entered into usage around the world because they are selectively toxic to arthropods and relatively non-toxic to vertebrates. It has been suggested tha...

Widespread occurrence of neonicotinoid insecticides in streams in a high corn and soybean producing region, USA.

Environ. Pollut. 193 , 189-96, (2014)

Neonicotinoid insecticides are of environmental concern, but little is known about their occurrence in surface water. An area of intense corn and soybean production in the Midwestern United States was...

 Synonyms

1H-Imidazol-4,5-d-2-amine, 1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydro-d-N-nitro-
Imidacloprid-d4
Imidazolidin-4,4,5,5-d4
1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro(H)-4,5-dihydro-1H-imidazol-2-amine