Tizanidine-d4 (hydrochloride)

Modify Date: 2024-01-11 23:07:30

Tizanidine-d4 (hydrochloride) Structure
Tizanidine-d4 (hydrochloride) structure
Common Name Tizanidine-d4 (hydrochloride)
CAS Number 1188263-51-5 Molecular Weight 294.20
Density N/A Boiling Point N/A
Molecular Formula C9H5D4Cl2N5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tizanidine-d4 (hydrochloride)


Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).

 Names

Name 5-chloro-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine,hydrochloride
Synonym More Synonyms

 Tizanidine-d4 (hydrochloride) Biological Activity

Description Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.

 Chemical & Physical Properties

Molecular Formula C9H5D4Cl2N5S
Molecular Weight 294.20
Exact Mass 293.02100
PSA 90.44000
LogP 2.35520

 Synonyms

Tizanidine-d4 Hydrochloride