CAY10581
Modify Date: 2024-01-30 17:20:46
CAY10581 structure
|
Common Name | CAY10581 | ||
|---|---|---|---|---|
| CAS Number | 1018340-07-2 | Molecular Weight | 363.406 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 548.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H21NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 285.7±30.1 °C | |
Use of CAY10581CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM[1][2]. |
| Name | cay10581 |
|---|---|
| Synonym | More Synonyms |
| Description | CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IDO:55 nM (IC50) |
| In Vitro | CAY10581 (100 nM; 24 小时) 消除 IFN-γ 在 MSCs 中的生长抑制[1]。 CAY10581 (化合物 36) 在 100 μM 浓度下 24 小时后对 T-REx 细胞活力的影响极小[2]。 Cell Viability Assay[1] Cell Line: Mesenchymal stem cells (MSCs) Concentration: 100 nM Incubation Time: 24 h post-treatment Result: Abrogated the growth inhibition by IFN-gamma (50 ng/ml) in MSCs. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 548.8±50.0 °C at 760 mmHg |
| Molecular Formula | C22H21NO4 |
| Molecular Weight | 363.406 |
| Flash Point | 285.7±30.1 °C |
| Exact Mass | 363.147064 |
| PSA | 75.63000 |
| LogP | 4.52 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.649 |
| 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-[(phenylmethyl)amino]-, (3S,4S)- |
| (3S,4S)-4-(Benzylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione |