2-Amino-1,3-bis(carboxylethoxy)propane HCl

Modify Date: 2024-01-18 23:58:37

2-Amino-1,3-bis(carboxylethoxy)propane HCl Structure
2-Amino-1,3-bis(carboxylethoxy)propane HCl structure
Common Name 2-Amino-1,3-bis(carboxylethoxy)propane HCl
CAS Number 1020112-73-5 Molecular Weight 235.23
Density N/A Boiling Point N/A
Molecular Formula C9H17NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Amino-1,3-bis(carboxylethoxy)propane HCl


2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Amino-1,3-bis(carboxylethoxy)propane
Synonym More Synonyms

  Biological Activity

Description 2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H17NO6
Molecular Weight 235.23

 Synonyms

MFCD31692207