Cephaloridine hydrate

Modify Date: 2025-08-22 10:55:11

Cephaloridine hydrate Structure
Cephaloridine hydrate structure
Common Name Cephaloridine hydrate
CAS Number 102039-86-1 Molecular Weight 433.50100
Density N/A Boiling Point N/A
Molecular Formula C19H19N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cephaloridine hydrate


Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].

 Names

Name (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,hydrate
Synonym More Synonyms

 Cephaloridine hydrate Biological Activity

Description Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].
Related Catalog
In Vitro Cephaloridine hydrate 可抑制金黄色葡萄球菌青霉素敏感菌株、青霉素耐药菌株、化脓性链球菌、肺炎链球菌、白喉棒状杆菌等,MIC 为 0.05-1 μg/mL[1]。
In Vivo Cephaloridine hydrate (50-500 mg/kg; 肌肉注射) 在兔和猴子中表现出剂量相关的肾毒性[2]。
References

[1]. P. W. Muggleton, et al. Laboratory Evaluation of a New Antibiotic-Cephaloridine (Ceporin). Br Med J. 1964 Nov 14;2(5419):1234-7.  

[2]. Perkins RL, et al. Cephaloridine and cephalothin: comparative studies of potential nephrotoxicity. J Lab Clin Med. 1968 Jan;71(1):75-84.  

 Chemical & Physical Properties

Molecular Formula C19H19N3O5S2
Molecular Weight 433.50100
Exact Mass 433.07700
PSA 156.19000

 Synonyms

Cephaloridine hydrate
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