A-940894

Modify Date: 2024-02-08 20:59:50

A-940894 Structure
A-940894 structure
Common Name A-940894
CAS Number 1027330-82-0 Molecular Weight 295.38200
Density N/A Boiling Point N/A
Molecular Formula C17H21N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A-940894


A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4). A-940894 exhibits with anti-inflammatory properties[1].

 Names

Name 4-piperazin-1-yl-6,7-dihydro-5H-benzo[1,2]cyclohepta[3,4-b]pyrimidin-2-amine
Synonym More Synonyms

 A-940894 Biological Activity

Description A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4). A-940894 exhibits with anti-inflammatory properties[1].
Related Catalog
Target

Ki: 7.6 nM (rat H4), 71 nM (human H4)[1].

References

[1]. M I Strakhova, et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. Br J Pharmacol. 2009 May;157(1):44-54.  

 Chemical & Physical Properties

Molecular Formula C17H21N5
Molecular Weight 295.38200
Exact Mass 295.18000
PSA 67.80000
LogP 1.94800

 Synonyms

2,4-diamino-5,6-disubstituted pyrimidine,9
UNII-8U5620H545
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.