Moracin P
Modify Date: 2024-01-08 10:11:10
Moracin P structure
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Common Name | Moracin P | ||
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| CAS Number | 102841-46-3 | Molecular Weight | 326.343 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 560.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H18O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 292.8±30.1 °C | |
Use of Moracin PMoracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3]. |
| Name | 5-(6-hydroxy-7,7-dimethyl-3a,4,5,6-tetrahydrofuro[3,2-g]chromen-2-yl)benzene-1,3-diol |
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| Synonym | More Synonyms |
| Description | Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3]. |
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| Related Catalog | |
| In Vitro | Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 560.6±50.0 °C at 760 mmHg |
| Molecular Formula | C19H18O5 |
| Molecular Weight | 326.343 |
| Flash Point | 292.8±30.1 °C |
| Exact Mass | 326.115417 |
| PSA | 83.06000 |
| LogP | 3.19 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.662 |
| Hazard Codes | Xi |
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| 5-(6-Hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)-1,3-benzenediol |
| 5-(6-hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)benzene-1,3-diol |
| 1,3-Benzenediol, 5-(6,7-dihydro-6-hydroxy-7,7-dimethyl-5H-furo[3,2-g][1]benzopyran-2-yl)- |
| Moracin P |