Kazinol F

Modify Date: 2024-01-12 07:39:49

Kazinol F Structure
Kazinol F structure
Common Name Kazinol F
CAS Number 104494-35-1 Molecular Weight 396.51900
Density 1.15g/cm3 Boiling Point 590ºC at 760mmHg
Molecular Formula C25H32O4 Melting Point N/A
MSDS N/A Flash Point 258.9ºC

 Use of Kazinol F


Kazinol F is a polyphenol from Broussonetia papyrifera. Kazinol F also is an effective Mpro inhibitor. Kazinol F has interaction with both the catalytic residues (His41 and Cys145) of Mpro and exhibits good binding affinity. Kazinol F can be used for the research of COVID-19[1].

 Names

Name 5-[3-(2,4-dihydroxyphenyl)propyl]-3,4-bis(3-methylbut-2-enyl)benzene-1,2-diol
Synonym More Synonyms

 Kazinol F Biological Activity

Description Kazinol F is a polyphenol from Broussonetia papyrifera. Kazinol F also is an effective Mpro inhibitor. Kazinol F has interaction with both the catalytic residues (His41 and Cys145) of Mpro and exhibits good binding affinity. Kazinol F can be used for the research of COVID-19[1].
Related Catalog
In Vitro Kazinol F 与 Mpro 的催化残基(His41 和 Cys145)相互作用,并表现出良好的结合亲和力 (-8.1kcal/mol)[1]。
References

[1]. Ghosh, Rajesh et al. Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches. J Biomol Struct Dyn. vol. 39,17 (2021): 6747-6760.  

 Chemical & Physical Properties

Density 1.15g/cm3
Boiling Point 590ºC at 760mmHg
Molecular Formula C25H32O4
Molecular Weight 396.51900
Flash Point 258.9ºC
Exact Mass 396.23000
PSA 80.92000
LogP 5.70170
Vapour Pressure 1.61E-14mmHg at 25°C
Index of Refraction 1.607

 Synonyms

Kazinol F