Procyanidin B-5 3,3'-di-O-gallate

Modify Date: 2024-01-21 18:24:25

Procyanidin B-5 3,3'-di-O-gallate Structure
Procyanidin B-5 3,3'-di-O-gallate structure
Common Name Procyanidin B-5 3,3'-di-O-gallate
CAS Number 106533-60-2 Molecular Weight 882.73
Density 1.96g/cm3 Boiling Point 1173.4ºC at 760mmHg
Molecular Formula C44H34O20 Melting Point N/A
MSDS N/A Flash Point 355.7ºC

 Use of Procyanidin B-5 3,3'-di-O-gallate


Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1].

 Names

Name [(2R,3R)-2-(3,4-dihydroxyphenyl)-6-[(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-4-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Synonym More Synonyms

 Procyanidin B-5 3,3'-di-O-gallate Biological Activity

Description Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1].
Related Catalog
References

[1]. Abe I, et al. Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis. Planta Med. 2000 Dec;66(8):753-6.  

 Chemical & Physical Properties

Density 1.96g/cm3
Boiling Point 1173.4ºC at 760mmHg
Molecular Formula C44H34O20
Molecular Weight 882.73
Flash Point 355.7ºC
Exact Mass 882.16400
PSA 354.28000
LogP 4.95800
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.915

 Synonyms

procyanidin B-5 3,3'-di-O-gallate
procyanidin B4
8)-epicatechin