Procyanidin B2 3,3'-di-O-gallate

Modify Date: 2024-01-11 18:30:09

Procyanidin B2 3,3'-di-O-gallate Structure
Procyanidin B2 3,3'-di-O-gallate structure
 Common Name Procyanidin B2 3,3'-di-O-gallate
CAS Number 79907-44-1 Molecular Weight 882.73
Density N/A Boiling Point N/A
Molecular Formula C44H34O20 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Procyanidin B2 3,3'-di-O-gallate


Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway[1].

 Names

Name B2-3,3'-di-O-gallate
Synonym More Synonyms

 Procyanidin B2 3,3'-di-O-gallate Biological Activity

Description Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway[1].
Related Catalog
References

[1]. Tyagi A, Kumar S, Raina K, Wempe MF, Maroni PD, Agarwal R, Agarwal C. Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells. Mol Carcinog. 2019 Jul;58(7):1105-1117.  

 Chemical & Physical Properties

Molecular Formula C44H34O20
Molecular Weight 882.73
Exact Mass 882.16400
PSA 354.28000
LogP 4.95800

 Synonyms

Procyanidin B2 3,3'-di-O-gallate
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