2-Acetyl-1H-pyrrole

Modify Date: 2024-01-02 16:09:01

2-Acetyl-1H-pyrrole Structure
2-Acetyl-1H-pyrrole structure
Common Name 2-Acetyl-1H-pyrrole
CAS Number 1072-83-9 Molecular Weight 109.126
Density 1.1±0.1 g/cm3 Boiling Point 220.9±13.0 °C at 760 mmHg
Molecular Formula C6H7NO Melting Point 88-93 °C(lit.)
MSDS Chinese USA Flash Point 92.4±27.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Acetyl-1H-pyrrole


2-Acetylpyrrole is a product of model browning systems, and has been isolated as a major flavour component of many foods[1]. 2-Acetylpyrrole has been used in the synthesis of 2-acetyl-1-pyrroline[2].

 Names

Name 2-acetylpyrrole
Synonym More Synonyms

 2-Acetyl-1H-pyrrole Biological Activity

Description 2-Acetylpyrrole is a product of model browning systems, and has been isolated as a major flavour component of many foods[1]. 2-Acetylpyrrole has been used in the synthesis of 2-acetyl-1-pyrroline[2].
Related Catalog
References

[1]. C J Wang, et al. Mutagenicity and cytotoxicity of nitropyrrole compounds derived from the reaction of 2-acetyl pyrrole with nitrite. Food Chem Toxicol. 1994 Sep;32(9):839-44.

[2]. Ron G. Buttery, et al. Cooked rice aroma and 2-acetyl-1-pyrroline. J. Agric. FoodChem. 1983, 31, 4, 823–826

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 220.9±13.0 °C at 760 mmHg
Melting Point 88-93 °C(lit.)
Molecular Formula C6H7NO
Molecular Weight 109.126
Flash Point 92.4±27.3 °C
Exact Mass 109.052765
PSA 32.86000
LogP 0.88
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.531

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OB5970000
CHEMICAL NAME :
Ketone, methyl pyrrol-2-yl
CAS REGISTRY NUMBER :
1072-83-9
BEILSTEIN REFERENCE NO. :
0001882
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H7-N-O
MOLECULAR WEIGHT :
109.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 321,213,1994

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H335
Precautionary Statements P261
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R22
Safety Phrases S37/39-S26-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS OB5970000
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles6

More Articles
Approaches of aroma extraction dilution analysis (AEDA) for headspace solid phase microextraction and gas chromatography-olfactometry (HS-SPME-GC-O): Altering sample amount, diluting the sample or adjusting split ratio?

Food Chem. 187 , 44-52, (2015)

Aroma extract dilution analysis (AEDA) is widely used for the screening of aroma-active compounds in gas chromatography-olfactometry (GC-O). In this study, three aroma dilution methods, (I) using diff...

Extension of a dynamic headspace multi-volatile method to milliliter injection volumes with full sample evaporation: Application to green tea.

J. Chromatogr. A. 1421 , 103-13, (2015)

An extension of multi-volatile method (MVM) technology using the combination of a standard dynamic headspace (DHS) configuration, and a modified DHS configuration incorporating an additional vacuum mo...

Mutagen formation in the reaction of Maillard browning products, 2-acetylpyrrole and its analogues, with nitrite.

Food Chem. Toxicol. 24(12) , 1303-8, (1986)

Three 2-substituted pyrroles (2-acetylpyrrole, pyrrole-2-carboxaldehyde and pyrrole-2-carboxylic acid), which are products of the Maillard browning reaction, were reacted with nitrite in buffer soluti...

 Synonyms

1-(1H-Pyrrol-2-yl)ethanone
2-Pyrrolyl methyl ketone
Methyl pyrrol-2-yl ketone
Methyl 2-pyrrolyl ketone
Ethanone, 1-(1H-pyrrol-2-yl)-
Pyrrol-2-yl methyl ketone
1-(2-Pyrrolyl)-1-ethanone
MFCD00005220
2-Acetyl pyrrole
EINECS 214-016-2
1-(1H-Pyrrol-2-yl)ethan-1-one
2-Acetylpyrrole
2-Acetyl-1H-pyrrole
ACETYL-2 PYRROLE
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