WIN 54954
Modify Date: 2025-08-27 20:39:21
WIN 54954 structure
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Common Name | WIN 54954 | ||
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| CAS Number | 107355-45-3 | Molecular Weight | 383.27 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H20Cl2N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of WIN 54954WIN 54954 is a broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections[1][2]. |
| Name | 5-{5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl}-3-methylisoxazole |
|---|---|
| Synonym | More Synonyms |
| Description | WIN 54954 is a broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections[1][2]. |
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| Related Catalog | |
| In Vitro | WIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL)[1].WIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC80 of 0.06 μg/mL[1]. |
| In Vivo | WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively[1]. |
| References |
| Molecular Formula | C18H20Cl2N2O3 |
|---|---|
| Molecular Weight | 383.27 |
| Exact Mass | 382.08500 |
| PSA | 56.85000 |
| LogP | 4.29400 |
| 5-<5-(2,6-dichloro-5-oxazolylphenoxy)pentyl>-3-methylisoxazole |
| 5-{5-[2,6-Dichloro-4-(4,5-dihydro-oxazol-2-yl)-phenoxy]-pentyl}-3-methyl-isoxazole |
| 5-(5-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methylisoxazole |
| WIN 54954 |
| Win 54954 |
| 5-{5-[2,6-Dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxyl]-pentyl}-3-methylisoxazole |