Ginkgolide J structure
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Common Name | Ginkgolide J | ||
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CAS Number | 107438-79-9 | Molecular Weight | 424.399 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 760.4±60.0 °C at 760 mmHg | |
Molecular Formula | C20H24O10 | Melting Point | 41-42 °C | |
MSDS | USA | Flash Point | 273.6±26.4 °C |
Use of Ginkgolide JGinkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2]. |
Name | Ginkgolide J |
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Synonym | More Synonyms |
Description | Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2]. |
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Related Catalog | |
In Vivo | Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons[1]. |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 760.4±60.0 °C at 760 mmHg |
Melting Point | 41-42 °C |
Molecular Formula | C20H24O10 |
Molecular Weight | 424.399 |
Flash Point | 273.6±26.4 °C |
Exact Mass | 424.136932 |
PSA | 148.82000 |
LogP | -0.68 |
Vapour Pressure | 0.0±5.8 mmHg at 25°C |
Index of Refraction | 1.651 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3.0 |
Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.
Magn. Reson. Chem. 50(8) , 569-75, (2012) The complete and unambiguous (1)H NMR assignments of ten marker constituents of Ginkgo biloba are described. The comprehensive (1)H NMR profiles (fingerprints) of ginkgolide A, ginkgolide B, ginkgolid... |
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Rapid analysis of terpene lactones in extract of Ginkgo biloba L. by high performance liquid chromatography.
Se Pu 18(5) , 394-7, (2000) A new rapid analytical method was developed for the quantification of terpene lactones (bilobalide(BB) and ginkgolide A, B, C, J) in extract of Ginkgo biloba L. (EGb) using a liquid-liquid solvent ext... |
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Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J.
Neurobiol. Aging 30(2) , 257-65, (2009) A new Ginkgo biloba extract P8A (TTL), 70% enriched with terpene trilactones, prevents A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices. This neu... |
6H-9,4a-(Epoxymethano)-3aH,9H-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1H)-trione, 11-(1,1-dimethylethyl)hexahydro-1,4b,10-trihydroxy-5-methyl-, (1R,3aR,4aR,4bR,5S,7aS,8aS,9S,10R,11S,11aS)- |
(1R,3R,6R,7S,8S,9R,10S,11S,13S,16S,17R)-6,9,17-Trihydroxy-16-methyl-8-(2-methyl-2-propanyl)-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione |
GinkgolideJ |
(1R,3R,6R,7S,8S,9R,10S,11S,13S,16S,17R)-8-tert-Butyl-6,9,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione |
Ginkgolid J |
7beta-hydroxyginkgolide a |