A 61603

Modify Date: 2023-01-19 02:11:22

A 61603 Structure
A 61603 structure
Common Name A 61603
CAS Number 107756-30-9 Molecular Weight 309.38400
Density N/A Boiling Point 548.4ºC at 760mmHg
Molecular Formula C14H19N3O3S Melting Point N/A
MSDS N/A Flash Point 285.5ºC

 Use of A 61603


A-61603 is a selective α1A-adrenergic receptor agonist[1]. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro[2].

 Names

Name N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide,hydrobromide

 A 61603 Biological Activity

Description A-61603 is a selective α1A-adrenergic receptor agonist[1]. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro[2].
Related Catalog
Target

α1A-adrenergic receptor

References

[1]. Meyer MD, et al. Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: A novel selective α1A receptor agonist. J. Med. Chem. 39(20), 4116-4119 (1996).

 Chemical & Physical Properties

Boiling Point 548.4ºC at 760mmHg
Molecular Formula C14H19N3O3S
Molecular Weight 309.38400
Flash Point 285.5ºC
Exact Mass 309.11500
PSA 99.17000
LogP 2.10350
Vapour Pressure 1.23E-12mmHg at 25°C