(D-Pro2,D-Trp6.8,Nle10)-Neurokinin B
Modify Date: 2025-08-24 11:34:07
(D-Pro2,D-Trp6.8,Nle10)-Neurokinin B structure
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Common Name | (D-Pro2,D-Trp6.8,Nle10)-Neurokinin B | ||
|---|---|---|---|---|
| CAS Number | 109212-72-8 | Molecular Weight | 1326.50000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C67H87N15O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (D-Pro2,D-Trp6.8,Nle10)-Neurokinin B(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1]. |
| Name | [D-Pro2, D-Trp6,8, Nle10]-Neurokinin B,DpHDFwVwL-Nle-NH2 |
|---|---|
| Synonym | More Synonyms |
| Description | (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1]. |
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| Related Catalog | |
| In Vivo | 在大鼠中，(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) 显着减少 Substance P- 和 Neurokinin B-， 但不减少乙酰胆碱或 Neurokinin A 诱导的流涎。(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 可将麻醉大鼠的血压降低 35% 至 40%[2]。 |
| References |
| Molecular Formula | C67H87N15O14 |
|---|---|
| Molecular Weight | 1326.50000 |
| Exact Mass | 1325.66000 |
| PSA | 457.08000 |
| LogP | 5.63230 |
| ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 |
| (D-PRO2,D-TRP6,8,NLE10)-NEUROKININ B |
| (D-Pro2,D-Trp6 |
| DPHDFWVWL-NLE-NH2 |
| H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 |