[D-Pro2,D-Phe7,D-Trp9]-Substance P
Modify Date: 2024-01-05 16:39:22
![[D-Pro2,D-Phe7,D-Trp9]-Substance P Structure](https://image.chemsrc.com/caspic/221/77275-70-8.png)
[D-Pro2,D-Phe7,D-Trp9]-Substance P structure
|
Common Name | [D-Pro2,D-Phe7,D-Trp9]-Substance P | ||
|---|---|---|---|---|
| CAS Number | 77275-70-8 | Molecular Weight | 1476.79000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C72H105N19O13S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of [D-Pro2,D-Phe7,D-Trp9]-Substance P[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2]. |
| Name | [D-Pro2,D-Phe7,D-Trp9]-Substance P |
|---|---|
| Synonym | More Synonyms |
| Description | [D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Substance P[2] |
| In Vitro | [D-Pro2,D-Phe7,D-Trp9] Substance P (10-100 μM; 2 min or 10 min) produces dose-related contractions of the guinea-pig ileum and in the rabbit external jugular vein[1]. |
| In Vivo | [D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure[2]. |
| References |
| Molecular Formula | C72H105N19O13S |
|---|---|
| Molecular Weight | 1476.79000 |
| Exact Mass | 1475.79000 |
| PSA | 557.72000 |
| LogP | 6.28670 |
| substance P,Pro(2)-Phe(7)-Trp(9) |
| Substance P,(D-Pro2,D-Phe7,D-Trp9) |
| ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2 |
| (D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P) |
| (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P |
| H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2 |