Ridogrel

Modify Date: 2024-01-02 15:03:17

Ridogrel structure	Common Name	Ridogrel
	CAS Number	110140-89-1	Molecular Weight	366.33400
	Density	1.26g/cm3	Boiling Point	495.2ºC at 760mmHg
	Molecular Formula	C₁₈H₁₇F₃N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	253.3ºC

Use of Ridogrel

Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities[1][2][3].

Name	Pentanoic acid, 5-[[(E)-[3-pyridinyl[3-(trifluoromethyl)phenyl]methylene]amino]oxy]
Synonym	More Synonyms

Description	Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities[1][2][3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
In Vitro	In rats, R 68 070 (1.25 mg/kg orally, -2 h) singly prolongs tail bleeding times as much as a combination of TXA2 synthetase inhibition (dazoxiben 10 mg/kg) and TXA2/prostaglandin endoperoxide receptor blockade (BM 13177 40 mg/kg). In dogs, the compound reduces coronary thrombosis induced by electrical damage (1.25 mg/kg i.v.) and prevents the evolution of occlusion/reperfusion-induced arrhythmias into ventricular fibrillation (2.5 mg/kg i.v.)[2.
References	[1]. De Clerck F, et al. R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivo. Thromb Haemost. 1989;61(1):43-49. [2]. Di Perri T, et al. Ridogrel, una nuova molecula antiaggregante piastrinica a doppio meccanismo d'azione. Profilo farmacologico e clinico [Ridogrel, a new platelet antiaggregant molecule with a double mechanism of action. A pharmacological and clinical profile]. Recenti Prog Med. 1991;82(10):533-540. [3]. Carty E, et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. Aliment Pharmacol Ther. 2000;14(6):807-817.

Density	1.26g/cm3
Boiling Point	495.2ºC at 760mmHg
Molecular Formula	C₁₈H₁₇F₃N₂O₃
Molecular Weight	366.33400
Flash Point	253.3ºC
Exact Mass	366.11900
PSA	71.78000
LogP	4.12430
Vapour Pressure	1.26E-10mmHg at 25°C
Index of Refraction	1.531

ethyl (E)-5-[[[...

CAS#:110169-17-0

Chloroform

CAS#:67-66-3

~41%

Ridogrel

CAS#:110140-89-1

Literature: US4746671 A1, ;

Precursor 2
CAS#:110169-17-0 ethyl (E)-5-[[[... CAS#:67-66-3 Chloroform
DownStream 0

ridogrel

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ridogrel
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Ridogrel
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-[[pyridin-3-yl-[3-(trifluoromethyl)phenyl]methylidene]amino]oxypenta noic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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