N-(p-amylcinnamoyl) Anthranilic Acid
Modify Date: 2025-08-25 09:53:47
N-(p-amylcinnamoyl) Anthranilic Acid structure
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Common Name | N-(p-amylcinnamoyl) Anthranilic Acid | ||
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| CAS Number | 110683-10-8 | Molecular Weight | 337.41 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 563.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H23NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 294.4±30.1 °C | |
Use of N-(p-amylcinnamoyl) Anthranilic AcidN-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker[1][2]. N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia[3]. |
| Name | aca |
|---|---|
| Synonym | More Synonyms |
| Description | N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker[1][2]. N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia[3]. |
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| Related Catalog | |
| Target |
PLA2[1][2]. TRP channel[1][2].Calcium-activated chloride channels[3]. |
| In Vitro | N-(p-amylcinnamoyl) Anthranilic Acid (ACA; 20 μM) completely blocks ADPR-induced whole-cell currents and H2O2-induced Ca2+ signals (IC50=1.7 μM) in HEK293cells transfected with human TRPM2[1]. N-(p-amylcinnamoyl) Anthranilic Acid (ACA; 20 μM) also blocks currents through human TRPM8 and TRPC6 expressed in HEK293 cells[1]. N-(p-amylcinnamoyl) Anthranilic Acid (ACA) modulates the activity of different TRP channels independent of PLA22 inhibition[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.1±50.0 °C at 760 mmHg |
| Molecular Formula | C21H23NO3 |
| Molecular Weight | 337.41 |
| Flash Point | 294.4±30.1 °C |
| Exact Mass | 337.167786 |
| PSA | 66.40000 |
| LogP | 7.11 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.629 |
| Storage condition | -20℃ |
| HS Code | 2924299090 |
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| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| 2-{[(2E)-3-(4-Pentylphenyl)-2-propenoyl]amino}benzoic acid |
| 4-amylcinnamoylanthranilicacid |
| 2-{[(2E)-3-(4-pentylphenyl)prop-2-enoyl]amino}benzoic acid |
| Benzoic acid, 2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]- |