diglyme

Modify Date: 2025-08-20 08:11:36

diglyme structure	Common Name	diglyme
	CAS Number	111-96-6	Molecular Weight	134.174
	Density	0.9±0.1 g/cm3	Boiling Point	159.8±0.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₄O₃	Melting Point	−64 °C(lit.)
	MSDS	Chinese USA	Flash Point	70.0±0.0 °C
	Symbol	GHS02, GHS08	Signal Word	Danger

Name	diglyme
Synonym	More Synonyms

Density	0.9±0.1 g/cm3
Boiling Point	159.8±0.0 °C at 760 mmHg
Melting Point	−64 °C(lit.)
Molecular Formula	C₆H₁₄O₃
Molecular Weight	134.174
Flash Point	70.0±0.0 °C
Exact Mass	134.094299
PSA	27.69000
LogP	-0.80
Vapour density	4.6 (vs air)
Vapour Pressure	3.2±0.2 mmHg at 25°C
Index of Refraction	1.394
InChIKey	SBZXBUIDTXKZTM-UHFFFAOYSA-N
SMILES	COCCOCCOC
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. May be air or light sensitive.
Water Solubility	Miscible

diglyme MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN3339000

CHEMICAL NAME :: Ether, bis(2-methoxyethyl)

CAS REGISTRY NUMBER :: 111-96-6

BEILSTEIN REFERENCE NO. :: 1736101

LAST UPDATED :: 199806

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C6-H14-O3

MOLECULAR WEIGHT :: 134.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 13680 mg/kg

SEX/DURATION :: male 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1100 ppm/6H

SEX/DURATION :: male 2 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 537 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1250 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1400 mg/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Dominant lethal test

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 1000 ppm/5D (Continuous)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB83-138198 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0698 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 191 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0698 No. of Facilities: 13 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 207 (estimated) No. of Female Employees: 52 (estimated)

Symbol	GHS02, GHS08
Signal Word	Danger
Hazard Statements	H226-H360
Supplemental HS	May form explosive peroxides.
Precautionary Statements	P201-P210-P280-P308 + P313-P370 + P378
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R10;R19;R60;R61
Safety Phrases	S53-S45
RIDADR	UN 3271 3/PG 3
WGK Germany	1
RTECS	KN3339000
Packaging Group	III
Hazard Class	3
HS Code	2909199090

Precursor 10
CAS#:67-56-1 Methanol CAS#:111-77-3 Methyl-PEG2-alcohol CAS#:111-46-6 Diethylene glycol CAS#:109-86-4 2-methoxyethanol
CAS#:433-06-7 2,2,2-trifluoro... CAS#:353-83-3 2-Iodo-1,1,1-tr... CAS#:17178-10-8 2-Methoxyethyl ... CAS#:74-88-4 methyl iodide
CAS#:112-35-6 m-PEG3-OH CAS#:124-41-4 Sodium Methylate
DownStream 10
CAS#:496-14-0 Phthalane CAS#:493-05-0 Isochroman CAS#:36101-23-2 α-methoxy-α,α'-... CAS#:5707-27-7 propyl 4-(4-eth...
CAS#:926-02-3 tert-butyl viny... CAS#:93-58-3 Methyl benzoate CAS#:939-55-9 2-Chloroethyl B... CAS#:41406-00-2 3-Isopropoxyaniline
CAS#:1883-38-1 tripentylborane CAS#:123-91-1 1,4-Dioxane

HS Code	2909199090
Summary	2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: diglyme
Price: Check
Purity: 99.5%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Methoxyethyl ether
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: diglyme
Price: ￥98.0/500ml
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

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diglyme

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