1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one

Modify Date: 2025-08-29 19:45:02

1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one structure	Common Name	1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one
	CAS Number	112501-42-5	Molecular Weight	265.26
	Density	1.4±0.1 g/cm3	Boiling Point	457.0±38.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₁NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	230.2±26.8 °C

Use of 1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one

Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1].

Name	Piperolactam A
Synonym	More Synonyms

Description	Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1].
Related Catalog	Research Areas >> Infection
Target	Leishmania
In Vitro	Piperolactam A 对杜氏利什曼原虫野生型、耐药和野外分离的无菌无鞭毛体细胞系具有抑制活性，IC50 值为 60 ± 9.6 μM (野生型)，分别为 121 ± 18 μM (抗 SSG)、109 ± 15 μM (抗 PMM) 和 87 ± 12 μM (野外分离株)[1]。
References	[1]. Bhattacharya P, et al. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta Trop. 2016 Jun;158:97-106.

Density	1.4±0.1 g/cm3
Boiling Point	457.0±38.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₁NO₃
Molecular Weight	265.26
Flash Point	230.2±26.8 °C
Exact Mass	265.073883
PSA	62.32000
LogP	2.34
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.776

Hazard Codes	Xi

1,2-Dimethoxydibenzo[cd,f]indol-4(5H)-one structure

1,2-Dimethoxydi...

CAS#:53948-09-7

~64%

1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one Structure

1-Hydroxy-2-met...

CAS#:112501-42-5

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2009/51417 A2, 2009 ; Location in patent: Page/Page column 18-19 ;

Precursor 1
CAS#:53948-09-7 1,2-Dimethoxydi...
DownStream 1
CAS#:53948-09-7 1,2-Dimethoxydi...

aristolactam FI

piperolactam-A

1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one

10-amino-4-hydroxy-3-methoxyphenanthrene-1-carboxylic acid lactam

Dibenz[cd,f]indol-4(5H)-one, 1-hydroxy-2-methoxy-

piperlactam A

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one
Price: ￥4800.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ARISTOLACTAM FI
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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