Bendamustine-d8
Modify Date: 2024-01-30 12:55:47
Bendamustine-d8 structure
|
Common Name | Bendamustine-d8 | ||
|---|---|---|---|---|
| CAS Number | 1134803-33-0 | Molecular Weight | 366.312 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 585.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H13D8Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 307.7±30.1 °C | |
Use of Bendamustine-d8Bendamustine-d8 is the deuterium labeled Bendamustine[1]. Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties[2]. |
| Name | 4-(5-{Bis[2-chloro(2H4)ethyl]amino}-1-methyl-1H-benzimidazol-2-yl)butanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Bendamustine-d8 is the deuterium labeled Bendamustine[1]. Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties[2]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 585.2±50.0 °C at 760 mmHg |
| Molecular Formula | C16H13D8Cl2N3O2 |
| Molecular Weight | 366.312 |
| Flash Point | 307.7±30.1 °C |
| Exact Mass | 365.151306 |
| LogP | 2.69 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.599 |
| 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl-1,1,2,2-d4)amino]-1-methyl- |
| 4-(5-{Bis[2-chloro(2H4)ethyl]amino}-1-methyl-1H-benzimidazol-2-yl)butanoic acid |