Urolithin B

Modify Date: 2024-01-02 18:32:28

Urolithin B Structure
Urolithin B structure
 Common Name Urolithin B
CAS Number 1139-83-9 Molecular Weight 212.20100
Density 1.395g/cm3 Boiling Point 432.6ºC at 760 mmHg
Molecular Formula C13H8O3 Melting Point N/A
MSDS N/A Flash Point 196.6ºC

 Use of Urolithin B


Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass[1][2].

 Names

Name 3-hydroxybenzo[c]chromen-6-one
Synonym More Synonyms

 Urolithin B Biological Activity

Description Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass[1][2].
Related Catalog
References

[1]. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57.

[2]. Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):583-597.

 Chemical & Physical Properties

Density 1.395g/cm3
Boiling Point 432.6ºC at 760 mmHg
Molecular Formula C13H8O3
Molecular Weight 212.20100
Flash Point 196.6ºC
Exact Mass 212.04700
PSA 50.44000
LogP 2.65180
Vapour Pressure 4.34E-08mmHg at 25°C
Index of Refraction 1.679

 Safety Information

HS Code 2914400090

 Synthetic Route

 Customs

HS Code 2914400090
Summary 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

urolithin-B
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Chemsrc provides Urolithin B(CAS#:1139-83-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Urolithin B are included as well.>> amp version: Urolithin B

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