Tripolin A

Modify Date: 2024-01-09 13:10:22

Tripolin A structure	Common Name	Tripolin A
	CAS Number	1148118-92-6	Molecular Weight	253.25274
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₁NO₃	Melting Point	265℃ (decomposition)
	MSDS	N/A	Flash Point	N/A

Use of Tripolin A

Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1].

Name	Tripolin A

Description	Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Aurora Kinase Signaling Pathways >> Cell Cycle/DNA Damage >> Aurora Kinase Research Areas >> Others
Target	IC50: 1.5 μM (Aurora A), 7 μM (Aurora A)[1].
In Vitro	Tripolin A induces mitotic spindle defects and spindle pole abnormalities[1].
References	[1]. Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP's Distribution on Microtubules. PLoS One. 2013;8(3):e58485.

Melting Point	265℃ (decomposition)
Molecular Formula	C₁₅H₁₁NO₃
Molecular Weight	253.25274

DC Chemicals Limited
China
Product Name: Tripolin A
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tripolin A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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